These symptoms may include high fever, headaches, swollen lymph nodes (which are a sign that distinguishes it from smallpox), muscle pain, and fatigue. TC: What are the symptoms of this disease?ĬB: Following a relatively long incubation (usually lasting around 6 to 13 days, and up to 21 days), it presents its first onset symptoms during a two-day period known as the “prodromal” phase. As for Europe, several patients are currently in hospital with the disease, but no death and no severe form of it have been detected on the continent.
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We must also keep in mind that these figures are taken from countries where medical care is somewhat lacking, particularly in more remote regions. Associated with more severe clinical forms, the Congo Basin strain has a case-fatality rate of around 10%. Both strains are now circulating in Cameroon: recently, cases of infections implying the West African strain – imported from Nigeria – have been reported.
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The second is the “Congo Basin” strain, which circulates in the Democratic Republic of the Congo (DRC), the Republic of the Congo, the Central African Republic (CAR), and Gabon. This is the one that was detected in the recent cases in Europe. The type that affects Nigeria, Liberia, Sierra Leone, and Côte d’Ivoire is the so-called West African strain, with a case-fatality rate between 1 to 3%. There are two strains of monkeypox that we know of. In 1970, the first human case of monkeypox was documented in a nine-month-old child in the Democratic Republic of the Congo, amid increasing efforts in the campaign to eradicate smallpox. The term “monkeypox” was coined when the virus was first identified in captive primates (in Denmark back in 1958), but in nature, the virus is most often found in squirrels and other rodents. And despite its name, the natural reservoir is not actually monkeys. However, smallpox only affected humans, which meant that we were able to eradicate it through worldwide mass vaccination, whereas monkeypox is carried by an animal viral reservoir.
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Like smallpox, it is a large DNA virus with a particular appetite for skin tissue. The Conversation: What exactly is the monkeypox virus?Ĭamille Besombes: Monkeypox is a virus belonging to the genus Orthopoxvirus, a family that also includes smallpox. She is currently conducting PhD research within the unit headed by the project’s coordinator, Arnaud Fontanet, a leading medical epidemiologist and emerging infectious disease specialist at the Pasteur Institute. But what is this virus? Who is affected? And should we be worried about the recent surge in cases? In a bid to answer such questions, we caught up with Camille Besombes, a medical doctor specialist in infectious diseases, who has been involved for the past three years in Afripox, a project that aims to gain a better understanding of the virus in its endemic region.
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